Six glasses of fresh orange juice or two cups of red bell pepper – what do they have in common? Each contains 500 milligrams (mg) of Vitamin C. While that’s five times more than the recommended dietary allowance of Vitamin C for adults (75to 90 mg daily), the findings of a recent meta-analysis suggest that this may be the ideal dose to help lower blood pressure.1
According to scientists at the John Hopkins Medical Research Center, 500 mg of Vitamin C may produce a modest decline in blood pressure.2 More long term studies are needed to confirm these findings but the evidence does suggest that Vitamin C may play a beneficial role in the clinical treatment of hypertension. This opens up a variety of natural supplement options for the more than 1 billion people around the world who suffer from hypertension or high blood pressure.3
Promising Results of Vitamin C Intake
Published in the American Journal of Clinical Nutrition, this meta-analysis is among the first to study the effects of Vitamin C on blood pressure. Data was collected from 29 randomized, controlled, previously published clinical trials that used an average dose of 500 mg of Vitamin C across a median trial period of 8 weeks. Systolic and/or diastolic blood pressure values were recorded in each of the trials and these values were also compared to a control group given a placebo. An average daily dose of 500 mg of vitamin C was seen to reduce systolic blood pressure by 3.84 mm Hg and diastolic blood pressure by 1.48 mm Hg. Among those already diagnosed with hypertension, the systolic reduction was nearly 5 mm of mercury (4.85 mm Hg) and the diastolic reduction was 1.67 mm Hg.
What is Vitamin C?
Vitamin C is a water-soluble vitamin and like all vitamins, it is needed in small quantities for our health and well-being. The body cannot store vitamin C and therefore a daily intake is necessary.4
Vitamin C is needed to make collagen, an important protein constituent of skin, cartilage, tendons, ligaments and blood vessels. It is required for the growth and repair of tissues, healing of wounds as well as the repair and maintenance of bones.5
Vitamin C is an antioxidant just like vitamins A and E and other plant-based nutrients. Antioxidants work at the cellular level by blocking some of the damage caused by free radical activity. Free radicals are substances that can damage the DNA of a cell causing cells to multiply abnormally. The build-up of free radical activity is believed to be the root cause of a number of degenerative diseases. In fact, the antioxidant properties of Vitamin C may explain why it has blood pressure-lowering properties.
Vitamin C – May Boost Benefits for Healthy Blood Pressure
Oxidative stress may affect the function of nitric oxide. Nitric oxide is a natural compound that helps to relax blood vessels. An adequate level of nitric oxide is essential for optimal blood function and to maintain normal, healthy blood pressure. As an antioxidant, Vitamin C helps to protect the level of nitric oxide in the body. A high dose of vitamin C, therefore, may improve nitric oxide’s biological activity and vascular function.5-6
Vitamin C in Your Heart Health Formulations
The latest statistics from the American Heart Association state that 76.4 million adults in the United States suffer from high blood pressure. That’s 1 in 3 American adults. High blood pressure raises the risk of other cardiovascular diseases such as heart disease, stroke, and congestive heart failure. About 35 percent of annual deaths in the United States are caused by cardiovascular disease and a death occurs every 39 seconds from cardiovascular-related causes.7-8
The subject of heart health is continually resonating with consumers and corresponds to an increase in consumer demand for heart health supplements.
Why manufacture heart health supplements?
Supplement business owners can play a role in meeting this crucial need by offering their customers a variety of heart health supplements that promote healthy blood pressure and cardiovascular health. A GMP-certified contract vitamin manufacturer can help you:
- Create scientifically-backed supplements that your customers will benefit from.
- Create attractive, eye-catching label designs to make your product stand out in the marketplace.
- Save time and money by providing order fulfillment and drop shipping services.
- Get your product to market faster by offering you in-house contract manufacturing solutions.
Partner with a nutraceutical manufacturer that possesses a track record of contract manufacturing success and has received recognition from leading business advocates for providing high quality supplement manufacturing services.
- Dietary Reference Intakes (DRIs): Recommended Intakes for Individuals, Vitamins, Food and Nutrition Board, Institute of Medicine, National Academies. iom.edu/Global/News%20Announcements/~/media/Files/Activity%20Files/Nutrition/DRIs/DRI_Summary_Listing.pdf
- Effects of vitamin C supplementation on blood pressure: a meta-analysis of randomized controlled trials, First published April 4, 2012, doi: 10.3945/ajcn.111.027995 Am J ClinNutrMay 2012ajcn.027995. ajcn.org/content/early/2012/04/03/ajcn.111.027995.abstract
- Raised Blood Pressure, World Health Organization. who.int/gho/ncd/risk_factors/blood_pressure_prevalence_text/en/
- Vitamin C (Ascorbic Acid), University of Maryland Medical Center. umm.edu/altmed/articles/vitamin-c-000339.htm
- Vitamin C, PubMed Health, U.S. National Library of Medicine. ncbi.nlm.nih.gov/pubmedhealth/PMH0003056/
- On the role of vitamin C and other antioxidants in atherogenesis and vascularDysfunction, ProcSocExpBiol Med. 1999 Dec;222(3):196-204. PMID: 10601878. ncbi.nlm.nih.gov/pubmed/10601878)
- The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxide, Free RadicBiol Med. 2000 Jun 15;28(12):1806-14. PMID: 10946222. ncbi.nlm.nih.gov/pubmed/10946222
- Cardiovascular Disease Statistics, John Hopkins Medicine, hopkinsmedicine.org/healthlibrary/conditions/adult/cardiovascular_diseases/cardiovascular_disease_statistics_85,P00243/)
- About High Blood Pressure, American Heart Association, heart.org/HEARTORG/Conditions/HighBloodPressure/AboutHighBloodPressure/About-High-Blood-Pressure_UCM_002050_Article.jsp)